Sildenafil and Tadalafil are both an oral tablet, prescription medicines that are FDA approved to treat erectile dysfunction (ED).

Sildenafil and Tadalafil are in a group of medications called phosphodiesterase 5 (PDE5) inhibitors. Sildenafil and Tadalafil treat ED by increasing blood flow to the penis during sexual stimulation, which leads to an erection. Sildenafil is taken one hour before sexual activity and its effects last 4-6 hours. Tadalafil can be taken up to 36 hours before sexual activity and therefore is often known as the “weekender”.

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Both medications should be taken with a full glass of water and can be taken on an empty stomach or with a normal-sized meal. It’s important to note that Sildenafil and Tadalafil will not give you an erection for the entire period that they are in your system. They simply allow you to achieve a satisfactory erection when you are sexually stimulated.

Sildenafil and Tadalafil are generally safe and well-tolerated by most men. However, like any medication, they can have side effects. Common side effects of ED medications may include:

For Sildenafil (all strengths) or Tadalafil (10mg or 20mg), take 1 tablet as needed for sexual activity. Do not take any more than is directed by your doctor. If you are taking daily Tadalafil (5mg), take your dose around the same time each day. If you miss a dose, take that dose once you remember if it’s still within the same-day. If you completely miss your daily dose, do not double up the next day. You can just get back on your normal dosing schedule as prescribed by your doctor.